CBD and Depression


Depression is a much more common psychiatric condition than you think. It can affect adults, young people, the elderly and even children.

It is estimated that depression affects 10/15% of the entire world population, we are talking about very high figures! It is not divided equally between men and women, who unfortunately suffer the most from it.

According to the WHO, depression will become the second incapacitating disease in the world only after cardiovascular disease, and already today it is among the top three reasons for suicide.

What is Depression?

But what is depression really?

Many think it is simply a mental illness or simple sadness, but in reality it is much more complex.

Depression affects the whole life of the person, from the emotional sphere, to the mood of the subject, on the body with physical symptoms and negatively affects social and working life.

The symptoms with which depression occurs can vary according to the depressive form that affects the patient and its severity, not to mention that there may also be a subjective variability from individual to individual.

Below we list the main and most common symptoms that are felt:

  • Persistent and accentuated low and sad mood
  • Frustration
  • Decreased interest and pleasure in carrying out any type of activity
  • Low self-esteem
  • Difficulty concentrating
  • Absence of sexual desire
  • Lack of appetite
  • Insomnia

Depression can also often be associated with anxiety and thoughts of suicide or self-harm

What to do in case of Depression?

The answer to this question is not simple.

Of course, the first thing to do would be to ask for help from the doctor, or from family, friends or confidants.

It is important to act from the first signs of the disease to ensure early diagnosis and timely intervention resulting in faster recovery.

Unfortunately, those who experience depressive feelings often tend not to seek help, perhaps for fear of being judged, out of shame or a form of rejection of this same disease.

Personal advice is to contact a professional as a psychologist or psychiatrist immediately, talk to those you trust, spouse, friends or relatives. Talking helps you, don't be ashamed, it's a disease and you need to heal.

How can CBD help us?

We assume that unfortunately CBD cannot cure depression, we need help from specialists and in the case of specific drugs.

But it can go a long way in relieving depressive states or brief anxieties.

The CBD molecule has shown promise in treating depression.

Few people know but the human body independently produces some cannabinoids, called endocannabinoids, assisted by the consumption of fatty acids found in fish, nuts and seeds.

Some studies show that CBD is able to interact with the human endocannabinoid system.

The endocannabinoid system regulates certain human functions such as mood, appetite and sleep.

CBD binds to specific receptors in the brain, endocannabinoids amplify the action of serotonin, a neurotransmitter that lifts mood and relieves stress.

Depression affects the production of seratonin or its reuptake by the receptors themselves.

Therefore, CBD reduces symptoms of depression by improving the activity of the receptors to which serotonin binds.

The effects of CBD on the endocannabinoid system, and its ability to release and optimize serotonin, are able to produce feelings of calm and relaxation typically associated with the intake of cannabidiol.

We can take CBD in various ways (as we had already reported in this article) the main ones are theCBD oil and the Cannabis Light.


A little science

Since we want to be a serious blog, each of our articles is always accompanied by scientific studies.

A 2010 study in laboratory mice showed that CBD acts as an "antidepressant, with effects comparable to those of certain drugs".
The mice underwent a swim test to assess the effects of CBD on motivation. The results showed that cannabidiol has positive effects on the physical activity of rats.

Those results were confirmed in 2016, when a similar animal study revealed CBD's effectiveness as an antidepressant. The test indicated that the rats were much more active and motivated after receiving CBD orally.

Research from 2011, with the aim of discovering the role of the endocannabinoid system in the alleviation of depression, also highlighted the beneficial effects of CBD.

The investigation revealed that "a lack of signals in the endocannabinoid system is sufficient to produce a depressive phenotype".

Research has found that by bridging this gap with CBD, it would be possible to treat symptoms of depression. It was enough to balance the endocannabinoid system with CBD to achieve effects similar to those of regular antidepressants.

A rat study conducted in 2016 found that serotonin and glutamate levels significantly increase after CBD administration.

Immediately after injecting CBD into the guinea pigs, the researchers noticed a "rapid antidepressant-like action".


Concluding after reading several scientific studies, above we have reported the latest developments. CBD can be a potential treatment for depression and anxiety.

The information contained in the Site is for informational purposes only, can be modified or removed at any time, and in any case in no case can it constitute the formulation of a diagnosis or the prescription of a treatment.

Leave a comment

Please note that comments are subject to approval before being posted

Welcome Newcomer